Browsing School of Medicine by Title
Now showing items 3118-3137 of 3148
-
Waist circumference provides an indication of numerous cardiometabolic risk factors in adults with cerebral palsy.
(2014)OBJECTIVE: To report the prevalence of cardiometabolic risk factors in a cohort of adults with cerebral palsy (CP) and to investigate the ability of anthropometric measures to predict these factors. DESIGN: Cross-sectional ... -
We Can Quit2 (WCQ2): a community-based intervention on smoking cessation for women living in disadvantaged areas of Ireland: a study protocol for a pilot cluster randomised controlled trial
(2019)Background: Tobacco use is the leading cause of preventable death in Ireland with almost 6000 smokers dying each year from smoking-related diseases. The ‘We Can Quit2’ (WCQ2) study is a pilot pragmatic two-arm, ... -
The We Can Quit2 Smoking Cessation Trial: Knowledge Exchange and Dissemination Following a Community-Based Participatory Research Approach
(2022)Background: 'We Can Quit2' pilot randomised controlled trial determined the feasibility [of conducting a community-based trial of We Can Quit, a peer-delivered stop-smoking programme (group support, combination nicotine ... -
The Wellcome trust UK-Irish bipolar affective disorder sibling-pair genome screen: first stage report
(Nature Publishing Group, 2002)We have completed the first stage of a two-stage genome wide screen designed to identify chromosomal regions that may harbour susceptibility genes for bipolar affective disorder. The first stage screening sample included ... -
Were Frailty Identification Criteria Created Equal? A Comparative Case Study on Continuous Non-Invasively Collected Neurocardiovascular Signals during an Active Standing Test in the Irish Longitudinal Study on Ageing (TILDA)
(2024)Background: In this observational study, we compared continuous physiological signals during an active standing test in adults aged 50 years and over, characterised as frail by three different criteria, using data from ... -
What do you think Dr Google? An Assessment of Online Information Concerning Smoking in Pregnancy
(2019)Introduction: Continuing to smoke during pregnancy remains a significant public health concern today. While health professionals offer advice and guidance, pregnant women increasingly look to other sources of information ... -
What does the ALSFRS-R really measure? A longitudinal and survival analysis of functional dimension subscores in amyotrophic lateral sclerosis
(2017)Introduction: ALSFRS-R is the most widely used functional rating system in ALS patients. However, heterogeneity in ALSFRS-R progression renders analysis challenging. We have explored the characteristics of total ALSFRS-R, ... -
What Explains Socioeconomic Differences in the Speed of Heart Rate Recovery to Postural Challenge?
(2017)Background: Much recent work has focused on the value of heart rate recovery (HRR) as a marker of cardiovascular health and a predictor of mortality. This article explores socioeconomic variation in HRR following exposure ... -
What have the genomics ever done for the psychoses?
(2010)Background: Despite the substantial heritability of the psychoses and their genuine public health burden, the applicability of the genomic approach in psychiatry has been strongly questioned or prematurely dismissed.Method ... -
What influences where they seek care? Caregivers' preferences for under-five child healthcare services in urban slums of Malawi: A discrete choice experiment
(2018)Access to and utilisation of quality healthcare promotes positive child health outcomes. However, to be optimally utilised, the healthcare system needs to be responsive to the expectations of the population it serves. ... -
What parents think about weaning. An island of Ireland study
(Safefood, 2018)The overall aim of this study was to investigate parents’ knowledge, attitudes and practices around weaning their infant to solid foods, with a focus on families who are at an economic or social disadvantage. The study ... -
When to Perform a Pancreatoduodenectomy in the Absence of Positive Histology? A consensus statement by the International Study Group of Pancreatic Surgery (ISGPS)
(2014)Pancreatoduodenectomy (PD) provides the best chance for cure in the treatment of patients with localized pancreatic head cancer. In patients with a suspected, clinically resectable pancreatic head malignancy, the need for ... -
White matter microstructure underlying default mode network connectivity in the human brain
(2010)Resting state functional magnetic resonance imaging (fMRI) reveals a distinct network of correlated brain function representing a default mode state of the human brain. The underlying structural basis of this functional ... -
Whole genome linkage scan of recurrent depressive disorder from the depression network study
(Oxford University Press, 2005)Genome-wide linkage analysis was carried out in a sample of 497 sib pairs concordant for recurrent major depressive disorder (MDD). There was suggestive evidence for linkage on chromosome 1p36 where the LOD score for ... -
Whole-cell but not acellular pertussis vaccines induce convulsive activity in mice: evidence of a role for toxin-induced interleukin-1 beta in a new murine model for analysis of neuronal side effects of vaccination
(American Society for Microbiology, 2001)Immunization with the whole-cell pertussis vaccine (Pw), while effective at preventing whooping cough in infants, has been associated with local, systemic, and neuronal reactions, including fevers and convulsions in children. ... -
Whole-genome sequencing improves discrimination of relapse from reinfection and identifies transmission events among patients with recurrent Clostridium difficile infections
(2015)Background: Recurrent Clostridium difficile infection (CDI) represents a significant healthcare challenge. Patients may suffer multiple episodes of CDI with the index strain (relapse) or become infected by another ... -
Women's compliance with current folic acid recommendations and achievement of optimal vitamin status for preventing neural tube defects.
(2011)BACKGROUND The timing of folic acid supplement usage is critical to preventing pregnancies affected by neural tube defects (NTDs) because the neural tube closes by Day 28 post-conception. We investigated compliance of ... -
Work like a Doc: A comparison of regulations on residents' working hours in 14 high-income countries
(2023)Background: Medical residents work long, continuous hours. Working in conditions of extreme fatigue has adverse effects on the quality and safety of care, and on residents' quality of life. Many countries have attempted ...
