Browsing School of Medicine by Title
Now showing items 1761-1780 of 3149
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Kaposi sarcoma in an patient with atopic dermatitis treated with ciclosporin.
(2013)There are four clinical subtypes of Kaposi sarcoma (KS): classic, endemic, epidemic and iatrogenic. The geographical prevalence of the endemic variant matches areas of human herpes virus type 8 (HHV8) seroprevalence. The ... -
Ketamine for depression: Clinical use and media accounts
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2021)This thesis comprises two research studies, one of which is a clinical trial. Study 1: Pilot randomised controlled trial: Ketamine as an adjunctive therapy for major depression, the Karma-Dep Trial (NCT03256162). The ... -
Key research questions for implementation of artificial intelligence in capsule endoscopy.
(2022)Background: Artificial intelligence (AI) is rapidly infiltrating multiple areas in medicine, with gastrointestinal endoscopy paving the way in both research and clinical applications. Multiple challenges associated with ... -
KH-Type Splicing Regulatory Protein Controls Colorectal Cancer Cell Growth and Modulates the Tumor Microenvironment
(2019)KH-type splicing regulatory protein (KHSRP) is a multifunctional nucleic acid binding protein implicated in key aspects of cancer cell biology: inflammation and cell-fate determination. However, the role KHSRP plays in ... -
The 'Kickstart to Recovery' programme; a quantitative evaluation of a football programme for mental health service users in an Irish context
(Trinity College Dublin. School of Medicine. Discipline of Occupational Therapy, 2020)Football is increasingly being used to support recovery and physical activity for mental health service users. The 'Kickstart to Recovery' programme is a collaboration between occupational therapy and the Football Association ... -
Kidney Function Estimated From Cystatin C, But Not Creatinine, Is Related to Objective Tests of Physical Performance in Community-Dwelling Older Adults
(2017)Background: The burden of chronic kidney disease is highest among older adults but the significance of a diminished level of kidney function in this heterogeneous population is poorly understood. We sought to examine ... -
The kinematics of phonotactic steering in the cricket Gryllus bimaculatus
(2011)Female crickets, Gryllus bimaculatus, are attracted by the male calling song and approach singing males; a behaviour known as phonotaxis. Even tethered females walking on a trackball steer towards a computer-generated male ... -
Klebsiella pneumoniae hijacks the Toll-IL-1R protein SARM1 in a type I IFN-dependent manner to antagonize host immunity.
(2022)Many bacterial pathogens antagonize host defense responses by translocating effector proteins into cells. It remains an open question how those pathogens not encoding effectors counteract anti-bacterial immunity. Here, we ... -
The knowledge exchange and dissemination plan of the We Can Quit2 community-based stop-smoking trial
(2021)We Can Quit2 was a community-based randomised controlled trial which determined the feasibility and acceptability of We Can Quit (WCQ), a peer delivered stop-smoking programme comprising group support and free Nicotine ... -
Knowledge, skills and attitudes of doctors towards assessing cognition in older patients in the emergency department.
(2013)PURPOSE OF THE STUDY: Although cognitive impairment and delirium are highly prevalent in older patients who present to the emergency department, multiple studies have highlighted inadequate detection by doctors. This ... -
L-Plastin Expression in HCT 116 Colorectal Cells increases migration and ROS in an NADPH Oxidase-dependent manner
(2022)Objective: L-plastin is an action-bundling protein normally expressed in cells of haemopoietic origin but is also associated with malignant transformation. Aberrant expression of L-plastin expression correlates with tumour ... -
Lack Of Association Between Angiotensin-converting Enzyme (Ace) Genotype And Essential Hypertension In Peruvian Older People
(2020)Background: Epidemiological studies have shown an association between the ACE gene I / D polymorphism with arterial hypertension, specifically the DD genotype in different populations. The objective of this study is to ... -
Lack of association between angiotensin-converting enzyme genotype and muscle strength in Peruvian older people
(2020)Aging can be associated with decreasing muscle strength, and related factors are comorbidities, sex, physical activity, and possibly genetic factors. Among genetic factors the renin-angiotensin system is of interest, but ... -
Lack of gender effect on familial schizophrenia. A Brazilian study.
(Arquivos de Neuro Psiquiatria / Academia Brasileira de Neurologia - ABNEURO, 2000)Estudos epidemiologicos em esquizofrenia estabeleceram que a idade de inicio para o genero masculino precede em alguns anos aquela para o feminino. No entanto, tal efeito de genero n?o vem sendo observado para os casos ... -
Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism
(2020)We present the largest exome sequencing study of autism spectrum disorder (ASD) to date (n = 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to integrate de novo and case-control rare variation, ... -
Laser speckle correlation as a non-contact ocular microtremor measurement technique
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2014)Ocular microtremor (OMT) is high frequency, low amplitude fixational eye movement present in all healthy people. It occurs even while the eye appears to be at rest. Benefits of measuring OMT have been proven in a number ... -
The Lasting Legacy of Childhood Adversity for Disease Risk In Later Life
(2015)Objective: There has been an increased interest in the role of the childhood social environment in the etiology of adult diseases in recent years. The present study examines whether the experience of adversity during ... -
LC3B globular structures correlate with survival in esophageal adenocarcinoma
(2015)Background Esophageal adenocarcinoma has the fastest growing incidence of any solid tumor in the Western world. Prognosis remains poor with overall five-year survival rates under 25 %. Only a limited number of patients ...
