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Molecular genetic evidence for overlap between general cognitive ability and risk for schizophrenia: a report from the Cognitive Genomics consorTium (COGENT).
(2014)
It has long been recognized that generalized deficits in cognitive ability represent a core component of schizophrenia (SCZ), evident before full illness onset and independent of medication. The possibility of genetic ...
Effects of a novel schizophrenia risk variant rs7914558 at CNNM2 on brain structure and attributional style.
(2014)
BACKGROUND:
A single nucleotide polymorphism (rs7914558) within the cyclin M2 (CNNM2) gene was recently identified as a common risk variant for schizophrenia. The mechanism by which CNNM2 confers risk is unknown.
AIMS:
To ...
Molecular pathways involved in neuronal cell adhesion and membrane scaffolding contribute to schizophrenia and bipolar disorder susceptibility.
(2011)
Susceptibility to schizophrenia and bipolar disorder may involve a substantial, shared contribution from thousands of common genetic variants each of small effect. Identifying if risk variants map to specific molecular ...
A NOS1 variant implicated in cognitive performance influences evoked neural responses during a hight density EEG study of early visual perception.
(Wiley Open Access, 2012)
Background: The nitric oxide synthasase‐1 gene (NOS1) has been implicated in mental disorders including schizophrenia and variation in cognition. The NOS1 variant rs6490121 identified in a genome wide association study of ...
Effects of MIR137 on fronto-amygdala functional connectivity.
(2014)
MIR137 is implicated in brain development and encodes a microRNA that regulates neuronal maturation and adult neurogenesis. Recently, a common genetic variant within MIR137 showed genome wide evidence of association with ...