Browsing Psychiatry by Subject "hippocampus"
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The hippocampus, amygdala and their principal output tracts in major depressive disorder
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2019)Major depressive disorder is a common, debilitating illness. Despite its high prevalence rate and global disease burden, the biological mechanisms underlying this disorder remain largely unknown. Evidence points towards ... -
How does the brain deal with cumulative stress? A review with focus on developmental stress, HPA axis function and hippocampal structure in humans
(2012)There is evidence that excessive stress exposure of the brain, mediated through the neurotoxic effects of cortisol and possibly neuroinflammation, causes damage to brain structure and function: the glucocorticoid cascade ...