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  • Brain Aβ load association and sexual dimorphism of plasma BACE1 concentrations in cognitively normal individuals at risk for AD 

    Bokde, Arun; Vergallo, Andrea; Houot, Marion; Cavedo, Enrica; Lemercier, Pablo; Vanmechelen, Eugeen; De Vos, Ann; Habert, Marie-Odile; Potier, Marie-Claude; Dubois, Bruno; Lista, Simone; Hampel, Harald; the INSIGHT-preAD study group; the Alzheimer Precision Medicine Intitiative (APMI) (2019)
    Introduction: Successful development of effective β-site amyloid precursor protein cleaving enzyme 1 (BACE1)–targeted therapies for early stages of Alzheimer's disease requires biomarker-guided intervention strategies ...