Browsing Surgery by Title
Now showing items 72-91 of 176
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Immunotoxicity Considerations for Next Generation Cancer Nanomedicines
(2019)Although interest and funding in nanotechnology for oncological applications is thriving, translating these novel therapeutics through the earliest stages of preclinical assessment remains challenging. Upon intravenous ... -
Impact of a new electronic handover system in surgery
(2011)Changing patterns of workflow in the hospital setting have highlighted the need for improvements in effective and safe handover of patient details. Financial constraints mean that hospitals are under increasing pressure ... -
In vitro assessment of primary human chondrocyte viability following treatment with intra-articular contrast agents and local anaesthetic
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2021)Title In vitro assessment of primary human chondrocyte viability following treatment with intra-articular contrast agents and local anaesthetic. Introduction Magnetic resonance (MR) and computed tomography (CT) direct ... -
Integrative multi-omic analytics for the early detection of pancreatic cancer
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2023)Pancreatic cancer (PC) has the lowest 5-year survival rate of any cancer, at just 12% in 2023. The poor survival rates observed in this cancer are the result of an accumulation of shortcomings and gaps in many aspects of ... -
Internal hernia following total gastrectomy with Roux-en-Y reconstruction.
(2011)Internal herniation is a well-described complication after a gastric bypass, particularly when performed laparoscopically, although it is rarely described following a total gastrectomy. A 55-year-old lady presented with ... -
Investigation into mitochondrial function and energy metabolism and their connectivity with protumourigenic cellular proceses in Barrett's oesophagus
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Surgery, 2016)Contemporary clinical management of Barrett’s oesophagus has highlighted the lack of accurate predictors of neoplastic progression. Currently all Barrett’s patients undergo surveillance, however, only a subset of patients ... -
Investigation of the link between obesity and breast cancer - the role of adipose tissue in the development and propagation of malignancy
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Surgery, 2010)Obesity and the metabolic syndrome are emerging risk factors for breast cancer. They are associated with increased incidence, an increased recurrence rate and a poorer prognosis. Despite this epidemiological evidence to ... -
Investigation of the molecular mechanisms underlying radioresistance in oesophageal cancer
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Surgery, 2011)The current standard of care for oesophageal cancer in Ireland involves neoadjuvant chemoradiation therapy (CRT) followed by surgery. Despite advances in treatment, resistance to neoadjuvant CRT remains a significant ... -
Ischaemic stroke or TIA in older subjects associated with impaired dynamic blood pressure control in the absence of severe large artery stenosis.
(2015)Background: older subjects may require higher baseline blood pressures to maintain cerebral perfusion. We investigated whether episodic hypotension is associated with tissue infarction in subjects with syncopal symptoms ...