Browsing School of Genetics & Microbiology by Subject "Schizophrenia"

Now showing items 1-3 of 3

    • The blood-brain barrier in neuropsychiatric disorders 

      GREENE, CHRIS (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2018)
      Schizophrenia is a severe and disabling mental disorder that affects approximately 1% of the population. Such is the heterogeneous nature of the disease that genetic, neurobiological and environmental factors all contribute ...

    • Claudin-5 expression at the Blood Brain Barrier and its therapeutic potential in neurological disease 

      O'Connor, Claire (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2023)
      Breakdown of the blood brain barrier's (BBB) integrity is a hallmark pathology in numerous neurological disorders. However, while research and therapeutic development has mostly focussed on neuronal function, the high ...

    • Interpretation and improvement of the current genetic epidemiology methodology for schizophrenia 

      RAMMOS, ALEXANDROS (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2018)
      Recent technological advancements have allowed for the development of new methodologies in the investigation of the genetic epidemiology of schizophrenia. Two of the most prominent methods in that field are the Polygenic ...