Browsing School of Genetics & Microbiology by Author "Deevy, Orla"

Now showing items 1-2 of 2

    • Exploring the functions of PRC2 in development and congenital disorders 

      Deevy, Orla (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2022)
      Polycomb group (PcG) proteins are key chromatin-based repressors of gene expression that play important roles in lineage-specification and cellular memory. PcG proteins assemble into multi-subunit complexes, termed Polycomb ...

    • PRC2 functions in development and congenital disorders 

      Bracken, Adrian; Deevy, Orla (2019)
      Polycomb repressive complex 2 (PRC2) is a conserved chromatin regulator that is responsible for the methylation of histone H3 lysine 27 (H3K27). PRC2 is essential for normal development and its loss of function thus results ...