Browsing Pharmacy and Pharmaceutical Sciences (Theses and Dissertations) by Subject "UDCA"

Now showing items 1-2 of 2

    • Chemical biology studies on human and mouse secondary bile acids 

      Lu, Yin (Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2022)
      Bile acids are important regulators of multiple homeostatic mechanisms integrating cell proliferation, metabolism and inflammation. The overall objective of this thesis was to use chemical biology tools to understand ...

    • Chemistry and Biology studies on anti-inflammiatory bile acid derivatives 

      LIU, SU (Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2019)
      Abstract The objective of the dissertation is to clarify the potency, cytotoxicity and metabolism of novel steroidal anti-inflammatory compounds in the treatment inflammatory bowel disease (IBD). Biochemical methods with ...