RSS 1.0Pharmacy and Pharmaceutical Sciences (Theses and Dissertations)
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The specialist pharmacist and quality indicators of medication use in the care of people with intellectual disabilities and behaviour disorders
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2016)Quality Medication Use and the Population with Intellectual Disabilities and Behaviour Disorders. A Modified Delphi Technique to develop Quality Indicators and a Grounded Theory approach to information provided by people ... -
The Gut-Brain Axis in Inflammatory Bowel Disease: Assessment of the Central Inflammatory Response to Dextran Sulfate Sodium-Induced Colitis in Rats
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2018)Inflammatory bowel disease (IBD) is a chronic relapsing-remitting inflammatory condition of the gastrointestinal (GI) tract. Evidence indicates a comorbidity between IBD and psychological symptoms in patients. It is thought ... -
Phytochemical studies on Choisya x dewitteana 'Aztec Pearl'
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2018)The thesis is introduced with a review of the genus Choisya. Here emphasis is placed on the botany, traditional uses, phytochemistry and ethnopharmacological studies. The main classes of compounds found in the genus are ... -
Targeting the NMDA receptor/NO signalling pathway following L-α aminoadipic acid-induced astrocytic impairment and associated changes in the structural plasticity of neurons
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2018)This investigation firstly aims to characterise the impact of astrocytic dysfunction on neurons in vitro, specifically the effects of L-α amino adipic acid (L-AAA)-induced astrocytic dysfunction on neurite outgrowth and ... -
Understanding the role of low glass transition temperature excipients in the mitigation of amorphisation on mechanical processing
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2017)Commonly employed pharmaceutical processes such as milling, blending and compaction may unintentionally lead to the generation of amorphous regions or metastable polymorphic forms in crystalline active pharmaceutical ...
