Browsing Pharmacy and Pharmaceutical Sciences (Theses and Dissertations) by Subject "TCIPA"

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  • Effect of 2-amino imidazoline derivatives on tumour cell-induced platelet aggregation 

    HUANG, YANNI (Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2020)
    Platelets play a central role in thrombosis and haemostasis. However, platelets can also aggregate in the presence of tumour cells in a phenomenon known as tumour-cell-induced-platelet-aggregation (TCIPA). During this ...

  • Role of kynurenine on platelet's function and beyond 

    AL-SHIBLAWI, NADHIM KAMIL (Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2020)
    Kynurenine is a metabolite of the amino acid tryptophan by the action of the tryptophan dioxygenase enzyme in the liver and the ubiquitous indolamine dioxygenase enzyme in other tissues. Although it has been shown that ...