Browsing Pharmacy and Pharmaceutical Sciences (Theses and Dissertations) by Subject "Pharmacology Pharmacy, Ph.D."
Now showing items 1-3 of 3
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A pharmacokinetic and clinical evaluation of antimicrobial drugs in critically ill patients during Continuous Venovenous Haemodifiltration (CVVHDF) therapy
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2007)Critically ill patients are at risk from sepsis requiring antimicrobial therapy and acute renal failure, which may require extracorporeal renal replacement therapy. The objective of this study was to quantify and assess ... -
The design, synthesis and biological effects of novel steroid prodrugs for treatment of gastrointestinal diseases
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2008)The aim of the work described in this thesis was to synthesize and test the biological effects of a novel type of prodrug to deliver steroids to the colon for the treatment of gastrointestinal diseases. Glucocorticoids are ... -
The development, validation and application of analytical methods for the analysis of drugs of abuse
(Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2001)There are five chapters presented in this thesis. The first chapter deals with development and validation of a HPLC method for the analysis of MDMA in illicitly produced Ecstasy tablets. In all 100 tablets were analysed ...