Browsing Pharmacy and Pharmaceutical Sciences (Theses and Dissertations) by Author "Coogan, Adrian"
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Design and synthesis of tubulin-binding agents, and their incorporation into novel dual-acting hybrid molecules targeting the tumour vasculature
Coogan, Adrian (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2013)This thesis involves the design and synthesis of tubulin binding agents, which aside from their anti-proliferative impact, seek to induce anti-vascular and anti-angiogenic responses on the unique vasculature derived by a ...