Browsing Genetics (Scholarly Publications) by Author "HOLLVILLE, EMILIE"
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Treatment with a BH3 mimetic overcomes the resistance of latency III EBV (+) cells to p53-mediated apoptosis.
HOLLVILLE, EMILIE (Nature, 2011)P53 inactivation is often observed in Burkitt's lymphoma (BL) cells due to mutations in the p53 gene or overexpression of its negative regulator, murine double minute-2 (MDM2). This event is now considered an essential ...