Browsing Genetics (Scholarly Publications) by Author "CHADDERTON, NAOMI SARAH"

Now showing items 1-2 of 2

    • Efficacy of codelivery of dual AAV2/5 vectors in the murine retina and hippocampus 

      HUMPHRIES, PETER; PALFI, ARPAD; CHADDERTON, NAOMI SARAH; FARRAR, GWYNETH JANE; KENNA, PAUL (2012)
      Recombinant adeno-associated virus (AAV) represents an efficient system for neuronal transduction. However, a potential drawback of AAV is its restricted packaging capacity of approximately 5kb. To bypass this limita- tion, ...

    • Mitochondrial disorders: aetiologies, models systems, and candidate therapies 

      MILLINGTON-WARD, SOPHIA; CHADDERTON, NAOMI SARAH; FARRAR, GWYNETH JANE; KENNA, PAUL (2013)
      It has become evident that many human disorders are characterised by mitochondrial dysfunction either at a primary level, due to mutations in genes whose encoded products are involved in oxidative phosphorylation, or at a ...