Browsing Pharmaceutical Chemistry (Theses and Dissertations) by Author "O'Boyle, Niamh"
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Synthesis, biochemical evaluation and structural studies of novel antiproliferative βeta-lactams
O'Boyle, Niamh (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2010)The synthesis and antiproliferative evaluation of anti-cancer β-lactams targeting tubulin, heat shock protein 90 and the estrogen receptor is described. Compounds were planned to include relevant substituents known to ...