Browsing Pharmaceutical Chemistry (Theses and Dissertations) by Author "Horan, Jason"
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Design, synthesis and biochemical evaluation of novel 1,2,3,4-tetrahydroisoquinolines as anti-proliferative agents in breast cancer cells
Horan, Jason (Trinity College (Dublin, Ireland). School of Pharmacy & Pharmaceutical Sciences, 2009)Isoquinolines are naturally occurring alkaloids that have shown biological activity in a number of different areas. In terms of breast cancer, tetrahydroisoquinoline based compounds have shown potential as selective estrogen ...