Browsing Microbiology (Scholarly Publications) by Subject "Microbiology"
Now showing items 1-20 of 48
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BABAR: an R package to simplify the normalisation of common reference design microarray-based transcriptomic datasets.
(BioMed Central, 2010)BACKGROUND: The development of DNA microarrays has facilitated the generation of hundreds of thousands of transcriptomic datasets. The use of a common reference microarray design allows existing transcriptomic data to be ... -
Bacterial DNA topology and infectious disease
(2009)he gram-negative bacterium Escherichia coli and its close relative Salmonella enterica have made important contributions historically to our understanding of how bacteria control DNA supercoiling and of how supercoiling ... -
Beta-neurexin is a ligand for the Staphylococcus aureus MSCRAMM SdrC
(2010)Gram-positive bacteria contain a family of surface proteins that are covalently anchored to the cell wall of the organism. These cell-wall anchored (CWA) proteins appear to play key roles in the interactions between ... -
A common theme in interaction of bacterial immunoglobulin-binding proteins with immunoglobulins illustrated in the equine system
(The American Society for Biochemistry and Molecular Biology, 2008)The M protein of Streptococcus equi subsp. equi known as fibrinogen-binding protein (FgBP) is a cell wall-associated protein with antiphagocytic activity that binds IgG. Recombinant versions of the seven equine IgG subclasses ... -
Complement regulator C4BP binds to Staphylococcus aureus surface proteins SdrE and Bbp inhibiting bacterial opsonization and killing.
(2013)Staphylococcus aureus is a premier human pathogen and the most common cause of osteoarticular, wound, and implanted device infections. We recently demonstrated S. aureus efficiently binds the classical complement regulator ... -
DNA supercoiling and the Lrp protein determine the directionality of fim switch DNA inversion in Escherichia coli K-12
(2006)Site-specific recombinases of the integrase family usually require cofactors to impart directionality in the recombination reactions that they catalyze. The FimB integrase inverts the Escherichia coli fim switch (fimS) in ... -
The effect of mobile element IS10 on experimental regulatory evolution in Escherichia coli
(2010)Mobile genetic elements are widespread in bacteria, where they cause several kinds of mutations. Although their effects are on the whole negative, rare beneficial mutations caused by insertion sequence elements are frequently ... -
Fibrinogen binding sites P336 and Y338 of clumping factor A are crucial for Staphylococcus aureus virulence.
(2008)We have earlier shown that clumping factor A (ClfA), a fibrinogen binding surface protein of Staphylococcus aureus, is an important virulence factor in septic arthritis. When two amino acids in the ClfA molecule, P336 and ... -
Fibronectin binding proteins are required for biofilm formation by community-associated methicillin resistant Staphylococcus aureus strain LAC
(2014)Community-associated methicillin-resistant Staphylococcus aureus of the USA300 lineage is emerging as an important cause of medical device-related infection. However, few factors required for biofilm accumulation by USA300 ... -
Fibronectin-binding protein B variation in Staphylococcus aureus
(2010)Background: Fibronectin binding proteins A and B (FnBPA and FnBPB) mediate adhesion of S.aureus to fibrinogen, elastin and fibronectin. We previously identified seven different isotopes of FnBPA based on divergence in the ...