RSS 1.0Microbiology (Scholarly Publications)
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Fibronectin binding proteins are required for biofilm formation by community-associated methicillin resistant Staphylococcus aureus strain LAC
(2014)Community-associated methicillin-resistant Staphylococcus aureus of the USA300 lineage is emerging as an important cause of medical device-related infection. However, few factors required for biofilm accumulation by USA300 ... -
Design and evaluation of antimalarial peptides derived from prediction of short linear motifs in proteins related to erythrocyte invasion
(2015)The purpose of this study was to investigate the blood stage of the malaria causing parasite, Plasmodium falciparum, to predict potential protein interactions between the parasite merozoite and the host erythrocyte and ... -
Immunophilin-protein interactions in Plasmodium falciparum.
(2015)Immunophilins comprise two protein families, cyclophilins (CYPs) and FK506-binding proteins (FKBPs), and are the major receptors for the immunosuppressive drugs cyclosporin A (CsA) and FK506 (tacrolimus), respectively. ... -
Two crystal structures of the FK506-binding domain of Plasmodium falciparum FKBP35 in complex with rapamycin at high resolution
(2015)Antimalarial chemotherapy continues to be challenging in view of the emergence of drug resistance, especially artemisinin resistance in Southeast Asia. It is critical that we identify novel anti-malarial drugs that inhibit ...
