Microbiology (Scholarly Publications)
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Aneuploidy influences the gene expression profiles in Saccharomyces pastorianus group I and II strains during fermentation
(2022)The lager yeasts, Saccharomyces pastorianus, are hybrids of Saccharomyces cerevisiae and Saccharomyces eubayanus and are divided into two broad groups, Group I and II. The two groups evolved from at least one common ... -
Packing a punch: Understanding how flavours are produced in lager fermentations
(2021)Beer is one of the most popular beverages in the world and it has an irreplaceable place in culture. Although invented later than ale, lager beers dominate the current market. Many factors relating to the appearance (colour, ... -
Population genomics of the pathogenic yeast Candida tropicalis identifies hybrid isolates in environmental samples
(2021)Candida tropicalis is a human pathogen that primarily infects the immunocompromised. Whereas the genome of one isolate, C. tropicalis MYA-3404, was originally sequenced in 2009, there have been no large-scale, multi-isolate ... -
Transcriptional Profile of the Industrial Hybrid Saccharomyces pastorianus Reveals Temperature-Dependent Allele Expression Bias and Preferential Orthologous Protein Assemblies
(2021)Saccharomyces pastorianus is a natural yeast evolved from different hybridization events between the mesophilic S. cerevisiae and the cold-tolerant S. eubayanus. This complex aneuploid hybrid carries multiple copies of the ... -
A Novel Method to Identify and Characterise Peptide Mimotopes of Heat Shock Protein 70-associated antigens
(2006)The heat shock protein, Hsp70, has been shown to play an important role in tumour immunity. Vaccination with Hsp70-peptide complexes (Hsp70-PCs), isolated from autologous tumour cells, can induce protective immune responses. ...