Browsing School of Chemistry by Sponsor "Health Research Board (HRB)"
Now showing items 1-6 of 6
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The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival
(2016)Barrett’s oesophagus (BO), an intestinal-type metaplasia (IM), typically arising in conjunction with gastro-oesophageal reflux disease, is a prominent risk factor for the development of oesophageal adenocarcinoma (OAC). ... -
Fluorescence imaging of bone cracks (microdamage) using visibly emitting 1,8-naphthalimide-based PET sensors
(2009)The ability of two 4-amino-1,8-naphthalimides (1 and 2) and anthracene (3) based photoinduced electron transfer (PET) sensors, previously developed in our laboratory, to function as selective imaging agents for exposed ... -
Platelets, photosensitizers and PDT
(2013)Photodynamic therapy (PDT) has both direct cell and indirect vascular effects. Both are well established and the latter has given rise to specifically target angiogenesis in PDT treatments. While the vascular effects are ... -
Porphyrin-magnetite nanoconjugates for biological imaging
(2011)Background: The use of silica coated magnetic nanoparticles as contrast agents has resulted in the production of highly stable, non-toxic solutions that can be manipulated via an external magnetic field. As a result, the ... -
Simple but powerful: Phenanthroline-based small molecules for cellular imaging and cancer screening
(2011)A two-step synthetic procedure gives highly fluorescent phenanthroline molecular probes. The compounds localize in the endoplasmic reticulum and their potential as bioactive probes was evaluated. The materials are quickly ... -
Transferrin conjugation does not increase the efficiency of liposomal Foscan during in vitro photodynamic therapy of oesophageal cancer
(2013)Photodynamic therapy (PDT) is based on the delivery of photocytotoxic agents to a target tissue, followed by irradiation. In order to increase the efficiency of PDT in oesophageal cancer therapy, polyethylene glycol ...