Browsing Medical Gerontology (Scholarly Publications) by Author "Kennelly, Sean"
Now showing items 1-9 of 9
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Characteristics and outcomes of older persons attending the emergency department: a retrospective cohort study.
O'Neill, Desmond; Romero-Ortuno, Roman; Coughlan, Tara; Kennelly, Sean (2014)Background: The analysis of routinely collected hospital data informs the design of specialist services for at-risk older people. Aim: Describe the outcomes of a cohort of older emergency department (ED) attendees and ... -
Does baseline hypotension predict incident depression in a cohort of community-dwelling older people? Data from The Irish Longitudinal Study on Ageing (TILDA)
Kenny, Rose; Kennelly, Sean; Briggs, Robert (2017)Background: hypotension is now recognised as a risk factor for syncope, cardiovascular events and mortality, but it may also represent a risk factor for late life depression (LLD). The aim of this study was to clarify ... -
European multicentre double-blind placebo-controlled trial of Nilvadipine in mild-to-moderate Alzheimer's disease - The substudy protocols: NILVAD frailty; NILVAD blood and genetic biomarkers; NILVAD cerebrospinal fluid biomarkers; NILVAD cerebral blood flow
Kenny, Rose; Lawlor, Brian; Kennelly, Sean; Walsh, Cathal (2016)Introduction In conjunction with the NILVAD trial, a European Multicentre Double-Blind Placebo Controlled trial of Nilvadipine in Mild-to-Moderate Alzheimer's disease (AD), there are four NILVAD substudies in which eligible ... -
Frequent inaccuracies in ABCD(2) scoring in non-stroke specialists' referrals to a daily Rapid Access Stroke Prevention service.
O'Neill, Desmond; Coughlan, Tara; Mc Cabe, Dominick; Kennelly, Sean; Collins, Daniel; Bradley, David (2013)Abstract The ‘accuracy’ of age, blood pressure, clinical features, duration and diabetes (ABCD2) scoring by non-stroke specialists referring patients to a daily Rapid Access Stroke Prevention (RASP) service is unclear, ... -
Longitudinal Association Between Orthostatic Hypotension at 30 Seconds Post-Standing and Late-Life Depression.
Kennelly, Sean; Kenny, Rose; Briggs, Robert (2018)There is an established cross-sectional association between orthostatic hypotension (OH) and late-life depression. The aim of this observational study was to clarify the longitudinal association between baseline symptomatic ... -
NILVAD protocol: a European multicentre double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease.
Walsh, Cathal; Kennelly, Sean; Lawlor, Brian; Kenny, Rose (2014)This study is a European multicentre, randomised, double-blind, placebo-controlled trial investigating the efficacy and safety of nilvadipine as a disease course modifying treatment for mild-to-moderate Alzheimer's disease ... -
Nilvadipine in mild to moderate Alzheimer's disease: a randomised controlled trial.
Coen, Robert; Kennelly, Sean; Kenny, Rose (2018)Background: This study reports the findings of the first large-scale Phase III investigator-driven clinical trial to slow the rate of cognitive decline in Alzheimer disease with a dihydropyridine (DHP) calcium channel ... -
Nursing home residents attending the emergency department: clinical characteristics and outcomes.
O'Neill, Desmond; Coughlan, Tara; Kennelly, Sean; Briggs, Robert (2013)Nursing home (NH) residents represent the frailest group of older people, and providing gerontologically attuned care that addresses these frailties is often a challenge within the emergency department (ED). This study ... -
Potentially inappropriate medication use in older adults with mild-moderate Alzheimer's disease: prevalence and associations with adverse events.
Kennelly, Sean; Lawlor, Brian; Kenny, Rose; Hutchinson, Siobhan; Dyer, Adam (2020)Aim: Potentially inappropriate medication (PIM) use is prevalent in older adults and is associated with adverse events, hospitalisation and mortality. We assessed the patterns and associations of PIM use in older adults ...