Browsing Medical Gerontology (Scholarly Publications) by Title
Now showing items 176-195 of 344
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The Importance of Age in the Prediction of Mortality by a Frailty Index: A Machine Learning Approach in the Irish Longitudinal Study on Ageing
(2021)The quantification of biological age in humans is an important scientific endeavor in the face of ageing populations. The frailty index (FI) methodology is based on the accumulation of health deficits and captures variations ... -
The Importance of Proximity to Death in Modelling Community Medication Expenditures for Older People: Evidence From New Zealand
(2014)BACKGROUND: Concerns about the long-term sustainability of health care expenditures (HCEs), particularly prescribing expenditures, has become an important policy issue in most developed countries. Previous studies suggest ... -
Improving the efficiency of multisensory integration in older adults: audio-visual temporal discrimination training reduces the susceptibility to the sound-induced flash illusion.
(2014)From language to motor control, efficient integration of information from different sensory modalities is necessary for maintaining a coherent interaction with the environment. While a number of training studies have focused ... -
In their own words: The voices of Older Irish people in the COVID-19 pandemic
(The Irish Longitudinal Study on Ageing, Trinity College Dublin, 2021)Since COVID-19 was declared an international pandemic by the World Health Organisation (WHO) in March 2020 (HSE, 2021), older people have carried the greatest burden of serious infection and death from the virus. ... -
Inappropriate prescribing in older fallers presenting to an Irish emergency department.
(2014)BACKGROUND: certain medications increase falls risk in older people. OBJECTIVE: to assess if prescribing modification occurs in older falls presenting to an emergency department (ED). DESIGN: before-and-after ... -
Incidence and prediction of falls in dementia: a prospective study in older
(2009)Background: Falls are a major cause of morbidity and mortality in dementia, but there have been no prospective studies of risk factors for falling specific to this patient population, and no successful falls interventio ... -
Increased endothelial activation in recently symptomatic versus asymptomatic carotid artery stenosis and in cerebral microembolic-signal-negative patient subgroups.
(2014)von Willebrand factor propeptide (VWF:Ag II) is potentially a more sensitive marker of acute endothelial activation than von Willebrand factor antigen (VWF:Ag). These biomarkers have not been simultaneously assessed in ... -
Increased platelet activation in early symptomatic versus asymptomatic carotid stenosis and relationship with microembolic status: Results from the Platelets And Carotid Stenosis (PACS) Study.
(2013)Abstract Background: Cerebral microembolic signals (MES) may predict increased stroke risk in carotid stenosis. However, the relationship between platelet counts or platelet activation status and MES in symptomatic ... -
Increased Salt Intake for Orthostatic Intolerance Syndromes: A Systematic Review and Meta-Analysis.
(2020)Guidelines recommend increased salt intake as a first-line recommendation in the management of symptomatic orthostatic hypotension and recurrent syncope. There have been no systematic reviews of this intervention. We sought ... -
Insights into the clinical management of the syndrome of supine hypertension - orthostatic hypotension (SH-OH): The Irish Longitudinal Study on Ageing (TILDA)
(2013)BACKGROUND: Our previously proposed morphological classification of orthostatic hypotension (MOH) is an approach to the definition of three typical orthostatic hemodynamic patterns using non-invasive beat-to-beat ... -
Integrating genotypic data with transcriptomic and proteomic data.
(2002)Historically genotypic variation has been detected at the phenotypic level, at the metabolic level, and at the protein chemistry level. Advances in technology have allowed its direct visualisation at the level of DNA ... -
Intergenerational Occupational Mobility and Objective Physical Functioning in Midlife and Older
(2018)Objective: This study investigates the relationship between intergenerational occupational mobility and objective physical functioning in later life. Method: Data come from The Irish Longitudinal Study of Ageing (TILDA), ... -
Interrupting Bedtime to Reverse Frailty Levels in Acute Care: A Study Protocol for the Breaking Bad Rest Randomized Controlled Trial
(2023)Background Hospitalized older patients spend most of the waking hours in bed, even if they can walk independently. Excessive bedrest contributes to the development of frailty and worse hospital outcomes. We describe the ... -
Investigation of the role of sleep and physical activity risk for chronic disease prevalence in older Irish adults
(2022)Background: Chronic diseases are the leading cause of death worldwide. Many of these diseases have modifiable risk factors, including physical activity and sleep, and may be preventable. This study investigated independent ... -
Involving older people in co-designing a primary-care intervention to reverse frailty and build resilience
(2021)Background: An essential consideration in health research is to conduct research with members of the public rather than for them. Public and patient involvement (PPI) of older people in research can improve enrolment, ... -
Is orthostatic hypotension more common in individuals with atrial fibrillation? – Findings from The Irish Longitudinal Study on Ageing (TILDA)
(2017)Introduction: atrial fibrillation (AF) and orthostatic hypotension (OH) share common risk factors such as age, hypertension and cardiovascular (CV) disease. The autonomic nervous system (ANS) also plays a role in the ...