Psychiatry (Theses and Dissertations): Recent submissions
Now showing items 1-5 of 72
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Exploring Neurocognitive Factors Underlying Autism and Hyperphagia in Prader-Willi Syndrome
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2024)Background: Prader-Willi Syndrome (PWS) is a rare complex multisystem genetic disorder recognised as the most common genetic cause of life-threatening obesity in humans (Butler, 1996). The PWS genotype gives rise to a ... -
Long-term outcomes following electroconvulsive therapy for treatment-resistant depression
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2016)Background: Electroconvulsive therapy (ECT) is the most acutely effective treatment for depression but its use is limited by high rates of early relapse and retrograde amnesia of uncertain severity and duration. Aims: ... -
Limbic System Development in Children and Adolescents with Attention Deficit/Hyperactivity Disorder: A Longitudinal Multimodal MRI Analysis
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2024)While Attention-Deficit Hyperactivity Disorder (ADHD) is characterized by age-related changes in symptoms and brain structures during childhood and adolescence, the link between brain structure and function is less clear. ... -
Deep Learning for Neuroimaging: Advancing Brain-Based Biomarkers of Autism Spectrum Disorder
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2023)In the last decade, deep learning (DL) has revolutionised fields like speech and vision through artificial neural networks. Can DL similarly transform biological psychiatry and neuroimaging? This thesis explores that ... -
The Contribution of Additional Genetic Variation to CNV Carrier Cognitive and Neurodevelopmental Outcomes
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2023)Many copy number variants (CNV) are strongly associated with neurodevelopmental disorders (NDDs) such as autism, intellectual disability/developmental delay (ID/DD) and schizophrenia. CNVs are large genomic deletions or ...