Browsing Physiology (Scholarly Publications) by Author "ROWAN, MICHAEL"
Now showing items 1-3 of 3
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Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization.
ANWYL, ROGER; KLYUBIN, IGOR; ROWAN, MICHAEL (2008)The current development of immunotherapy for Alzheimer's disease is based on the assumption that human-derived amyloid beta protein (Abeta) can be targeted in a similar manner to animal cell-derived or synthetic Abeta. ... -
Beta-amyloid-mediated inhibition of NMDA receptor-dependent long-term potentiation induction involves activation of microglia and stimulation of inducible nitric oxide synthase and superoxide
ANWYL, ROGER; ROWAN, MICHAEL (2004)The mechanisms underlying the inhibition of long-term potentiation (LTP) induction by amyloid -peptide (A ) were investigated in the medial perforant path of the rat and mouse dentate gyrus in vitro . Evidence ... -
Removal of Synaptic Ca2+-Permeable AMPA Receptors during Sleep.
ULRICH, DANIEL; ROWAN, MICHAEL (2011)here is accumulating evidence that sleep contributes to memory formation and learning, but the underlying cellular mechanisms are incompletely understood. To investigate the impact of sleep on excitatory synaptic transmission, ...