Browsing Physiology (Scholarly Publications) by Author "LYONS, ANTHONY"
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Atorvastatin prevents age-related and amyloid-beta-induced microglial activation by blocking interferon-gamma release from natural killer cells in the brain
LYONS, ANTHONY; LYNCH, MARINA (2011)Abstract: Background: Microglial function is modulated by several factors reflecting the numerous receptors expressed on the cell surface, however endogenous factors which contribute to the age-related increase in microglial ... -
Long-term potentiation is impaired in CD200-deficient mice: a role for Toll-like receptor activation.
LYNCH, MARINA; COSTELLO, DEREK; COX, FRANCES FIONNUALA; BROWNE, TARA; DENIEFFE, STEPHAINE; LYONS, ANTHONY (2011)The membrane glycoprotein CD200 is expressed on several cell types including neurons whereas expression of its receptor, CD200R, is restricted principally to cells of the myeloid lineage, including microglia. The interaction ...