Browsing Physiology (Scholarly Publications) by Author "Kerskens, Christian"
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The age-related deficit in LTP is associated with changes in perfusion and blood-brain barrier permeability.
Kerskens, Christian; Lynch, Marina; Kelly, Aine (2012)In view of the increase in the aging population and the unavoidable parallel increase in the incidence of age-related neurodegenerative diseases, a key challenge in neuroscience is the identification of clinical signatures ... -
Elucidating the complex organization of neural micro-domains in the locust Schistocerca gregaria using dMRI
Witney, Alice; Kerskens, Christian (2021)To understand brain function it is necessary to characterize both the underlying structural connectivity between neurons and the physiological integrity of these connections. Previous research exploring insect brain ... -
Iron accumulation in microglia triggers a cascade of events that leads to altered metabolism and compromised function in APP/PS1 mice.
Lynch, Marina; Kerskens, Christian; McIntosh, Allison; Mela, Virginia; Harty, Conor; Minogue, Aedin M.; Costello, Derek A.; Kerskens, Christian; Lynch, Marina A. (2019)Among the changes that typify Alzheimer’s disease (AD) are neuroinflammation and microglial activation, amyloid deposition perhaps resulting from compromised microglial function and iron accumulation. Data from Genome Wide ...