dc.contributor.advisor | Gunnlaughsson, Thorfinnur | |
dc.contributor.author | Banerjee, Swagata | |
dc.date.accessioned | 2019-10-17T10:54:37Z | |
dc.date.available | 2019-10-17T10:54:37Z | |
dc.date.issued | 2012 | |
dc.identifier.citation | Swagata Banerjee, 'Synthesis, photophysical and DNA binding studies of novel pyridinium based 1 ,8-naphthalimide derivatives', [thesis], Trinity College (Dublin, Ireland). School of Chemistry, 2012, pp 330 | |
dc.identifier.other | THESIS 10008 | |
dc.identifier.uri | http://hdl.handle.net/2262/89778 | |
dc.description.abstract | This thesis entitled "Synthesis, Photophysical and DNA Binding Studies of Novel
Pyridinium Based 1,8-Naphthalimide Derivatives" is divided into six chapters. Chapter 1 is
the introductory chapter, which provides a brief introduction to the cell cycle and how
misregulation of cell cycle can lead to cancer development. This is followed by a brief
description of the DNA structure, different binding modes by which small molecules can
interact with DNA and a summary of various methods widely used to probe drug-DNA
interactions. The development of various antitumour agents based on the 1,8-
naphthalimide structure is presented citing relevant examples from the literature and also
work performed within the Gunnlaugsson group. The photophysical properties of various
1,8-naphthalimide derivatives are also discussed. | |
dc.format | 1 volume | |
dc.language.iso | en | |
dc.publisher | Trinity College (Dublin, Ireland). School of Chemistry | |
dc.relation.isversionof | http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb15349379 | |
dc.subject | Chemistry, Ph.D. | |
dc.subject | Ph.D. Trinity College Dublin. | |
dc.title | Synthesis, photophysical and DNA binding studies of novel pyridinium based 1 ,8-naphthalimide derivatives | |
dc.type | thesis | |
dc.type.supercollection | thesis_dissertations | |
dc.type.supercollection | refereed_publications | |
dc.type.qualificationlevel | Doctoral | |
dc.type.qualificationname | Doctor of Philosophy (Ph.D.) | |
dc.rights.ecaccessrights | openAccess | |
dc.format.extentpagination | pp 330 | |
dc.description.note | TARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie | |