A microcantilever-based, dual-mode, quantitative sensing platform for investigation of biological interactions
Citation:
Jason Jensen, 'A microcantilever-based, dual-mode, quantitative sensing platform for investigation of biological interactions', [thesis], Trinity College (Dublin, Ireland). School of Physics, 2013, pp 204Download Item:
Jensen TCD THESIS 9975 A microcantilever based.pdf (PDF) 109.3Mb
Abstract:
Since the introduction of the atomic force microscope (AFM) and the subsequent availability of high-quality cantilevers the interest in the application of microcantilevers as biosensors has increased year-on-year. Much of the work using these sensors involves working in either the static or the dynamic mode, however there is little work described in the literature involving the use of the two modes in parallel. This thesis describes the development of a dual-mode microcantilever-based sensing platform for applications of quantitative biosensing in a liquid. Due to the large damping of the liquid the application of the dual-mode device for the detection of small biomolecules in low concentration requires the use of a mass label which can increase the sensitivity of the device.
Author: Jensen, Jason
Advisor:
Hegner, MartinQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). School of PhysicsNote:
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Full text availableKeywords:
Physics, Ph.D., Ph.D. Trinity College DublinLicences: