The characterisation of peripheral blood and intestinal antigen presenting cells in coeliac disease
Citation:
Louise Elliott, 'The characterisation of peripheral blood and intestinal antigen presenting cells in coeliac disease', [thesis], Trinity College (Dublin, Ireland). Department of Immunology, 2013, pp 301Download Item:
Abstract:
Antigen presenting cells, part of the innate immune system, play a central role in initiating and modulating the adaptive immune response. Coeliac disease is caused by aberrant activity of T cells specific for the dietary antigen gliadin that results in a complex inflammatory cascade, causing mucosal damage and villous atrophy. The overall objective of this thesis was to gain a better understanding of the role of antigen presenting cells in the immunopathogenesis of coeliac disease and the significance of tTG and CD163 expression in the coeliac lesion.
Author: Elliott, Louise
Advisor:
Feighery, ConlethQualification name:
Doctor of Philosophy (Ph.D.)Publisher:
Trinity College (Dublin, Ireland). Department of ImmunologyNote:
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Full text availableKeywords:
Immunology, Ph.D., Ph.D. Trinity College DublinMetadata
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