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  The Pharmacokinetic Interaction between Ivacaftor and Ritonavir 

  LIDDY, ANNE MARIE (Trinity College Dublin. School of Medicine. Discipline of Pharmacology & Therapeutics, 2019)

  Ivacaftor is the first small molecule for the treatment of cystic fibrosis (CF) that directly targets the inherited defect in the cystic fibrosis transmembrane conductance regulator (CFTR). In phase III clinical trials ...
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  The nerve of facial expression, impact of its anatomical variations on iatrogenic surgical injury and a novel MRI diffusion weighted imaging technique to image its intra-parotid course 

  EL KININY, WALID HOSAM (Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2018)

  This doctorate in clinical medicine set out to assess how variations in facial nerve anatomy to the intra-parotid venous system could impact on surgical access to the parotid gland or the mandible, and explored methods to ...
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  Examining links between Factor Xa, endothelial dysfunction, adverse pregnancy outcomes and cardiovascular disease in Lupus 

  MURPHY, CLAIRE-LOUISE MARIE (Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2018)

  Systemic lupus erythematosus (SLE) is a multisystemic autoimmune rheumatic disease (ARD) associated with significant morbidity and mortality, which presents mainly in women of childbearing age. Women with SLE have a 5-10-fold ...
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  A role for interleukin-1β in synaptic function 

  Vereker, Emily (Trinity College (Dublin, Ireland). Department of Physiology, 2001)

  The proinflammatory cytokine, interleukin-1β (IL -1β ). one of the most extensively studied cytokines to date, is known to play a pivotal role in neurodegenerative, inflammatory and infectious diseases. Moreover, IL-1β has ...
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  Mental health in Northern Malawi : a cultural perspective 

  Smyth, Karen M. (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2002)

  This thesis seeks to address a theoretical question: What is the experience of people with a mental disturbance, when they are introduced to a health care system which is ontologically distinct from their own cultural ...

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