Browsing Microbiology by Subject "Genetics"
Now showing items 1-8 of 8
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Evolutionary Genomics of Staphylococcus aureus Reveals Insights into the Origin and Molecular Basis of Ruminant Host Adaptation
(Oxford University Press, 2010)Phenotypic biotyping has traditionally been used to differentiate bacteria occupying distinct ecological niches such as host species. For example, the capacity of Staphylococcus aureus from sheep to coagulate ruminant ... -
The nucleoid-associated protein HU controls three regulons that coordinate virulence, response to stress and general physiology in Salmonella enterica serovar Typhimurium
(2011)The role of the HU nucleoid-associated proteins in gene regulation was examined in Salmonella enterica serovar Typhimurium. The dimeric HU protein consists of different combinations of its ? and ? subunits. Transcriptomic ... -
Packing a punch: Understanding how flavours are produced in lager fermentations
(2021)Beer is one of the most popular beverages in the world and it has an irreplaceable place in culture. Although invented later than ale, lager beers dominate the current market. Many factors relating to the appearance (colour, ... -
The PolyA tail length of yeast histone mRNAs varies during the cell cycle and is influenced by Sen1p and Rrp6p
(2012)Yeast histone mRNAs are polyadenylated, yet factors such as Rrp6p and Trf4p, required for the 3?-end processing of non-polyadenylated RNAs, contribute to the cell cycle regulation of these transcripts. Here, we investigated ... -
Protein A Is Released into the Staphylococcus aureus Culture Supernatant with an Unprocessed Sorting Signal.
(2015)The immunoglobulin binding protein A (SpA) of Staphylococcus aureus is synthesized as a precursor with a C-terminal sorting signal. The sortase A enzyme mediates covalent attachment to peptidoglycan so that SpA is displayed ... -
Rational design of an artificial genetic switch: co-option of the H-NS-repressed proU operon by the VirB virulence master regulator
(2011)The H-NS protein represses the transcription of hundreds of genes in Gram-negative bacteria. De-repression is achieved by a multitude of mechanisms, many of which involve binding of a protein to DNA at the repressed promoter ... -
Regulation of transcription by DNA supercoiling in Mycoplasma genitalium: global control in the smallest known self-replicating genome.
(2011)The mollicute Mycoplasma genitalium causes sexually transmitted disease in humans. It has recently come to widespread public attention through its involvement in pioneering synthetic biology experiments. The 580-kilo-base-pair ... -
Transposable temperate phages promote the evolution of divergent social strategies in Pseudomonas aeruginosa populations
(2019)Transposable temperate phages randomly insert into bacterial genomes, providing increased supply and altered spectra of mutations available to selection, thus opening alternative evolutionary trajectories. Transposable ...