Browsing Microbiology by Author "Corr, Sinead"
Now showing items 1-6 of 6
-
Establishing Boundaries: The Relationship That Exists between Intestinal Epithelial Cells and Gut-Dwelling Bacteria.
Corr, Sinead (2019)The human gastrointestinal (GI) tract is a highly complex organ in which various dynamic physiological processes are tightly coordinated while interacting with a complex community of microorganisms. Within the GI tract, ... -
IL-33 and IL-18 in inflammatory bowel disease etiology and microbial interactions
Corr, Sinead (2019)The IL-1 cytokines are a newly expanded family, with each of its 11 members playing an important role in health and disease. Typically acting as pro- or anti-inflammatory mediators of first-line innate immunity, their ... -
Lactobacillus spp. for Gastrointestinal Health: Current and Future Perspectives
Corr, Sinead (2022)In recent decades, probiotic bacteria have become increasingly popular as a result of mounting scientific evidence to indicate their beneficial role in modulating human health. Although there is strong evidence associating ... -
Loss of microRNA-21 influences the gut microbiota causing reduced susceptibility in a murine model of colitis.
Corr, Sinead; O'Neill, Luke; Johnston, Daniel (2018)Background and aims: microRNAs regulate gene expression and influence the pathogenesis of human diseases. The present study investigated the role of microRNA-21 [miR-21] in the pathogenesis of intestinal inflammation, ... -
MicroRNA-21 Limits Uptake of Listeria monocytogenes by Macrophages to Reduce the Intracellular Niche and Control Infection.
Corr, Sinead; O'Neill, Luke; Johnston, Daniel (2017)MiRNAs are important post-transcriptional regulators of gene expression. MiRNA expression is a crucial part of host responses to bacterial infection, however there is limited knowledge of their impact on the outcome of ... -
NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease
Corr, Sinead (2018)Anti-microbial signaling pathways are normally triggered by innate immune receptors when detecting pathogenic microbes to provide protective immunity. Here we show that the inflammasome sensor Nlrp1 aggravates DSS-induced ...