Browsing Microbiology by Author "BOND, URSULA"
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The complex and dynamic genomes of industrial yeasts
BOND, URSULA (2009)The Saccharomyces sensu stricto genus contains many species that are industrially important for fermentation of wines, beers and ales. The molecular characterization of the genomes of yeasts involved in these processes ... -
Deletion of the nuclear exosome component RRP6 leads to continued accumulation of the histone mRNA HTB1 in S-phase of the cell cycle in Saccharomyces cerevisiae.
BOND, URSULA (2007)The nuclear exosome, a macromolecular complex of 3 ’ to 5 ’ exonucleases, is required for the post- transcriptional processing of a variety of RNAs including rRNAs and snoRNAs. Additionally, this complex forms part ... -
Engineering Saccharomyces pastorianus for the co-utilisation of xylose and cellulose from biomass.
BOND, URSULA (2015)Background Lignocellulosic biomass is a viable source of renewable energy for bioethanol production. For the efficient conversion of biomass into bioethanol, it is essential that sugars from both the cellulose and ... -
Metabolic engineering of yeasts by heterologous enzyme production for degradation of cellulose and hemicellulose from biomass: a perspective
BOND, URSULA (2014)This review focuses on current approaches to metabolic engineering of ethanologenic yeast species for the production of bioethanol from complex lignocellulose biomass sources. The experimental strategies for the degradation ... -
Molecular Mimics of the Tumour Antigen MUC1
BOND, URSULA; JAMES, THARAPPEL (2012)A key requirement for the development of cancer immunotherapy is the identification of tumour-associated antigens that are differentially or exclusively expressed on the tumour and recognized by the host immune system. ... -
The PolyA tail length of yeast histone mRNAs varies during the cell cycle and is influenced by Sen1p and Rrp6p
JAMES, THARAPPEL; BOND, URSULA (2012)Yeast histone mRNAs are polyadenylated, yet factors such as Rrp6p and Trf4p, required for the 3?-end processing of non-polyadenylated RNAs, contribute to the cell cycle regulation of these transcripts. Here, we investigated ... -
Recombination between Homeologous Chromosomes in Lager Yeasts leads to Loss of Function of the Hybrid GPH1 Gene.
BOND, URSULA (2009)Yeasts used in the production of lagers contain complex allopolyploid genomes, resulting from the fusion of two different yeast species closely related to Saccharomyces cerevisiae and Saccharomyces bayanus. Recombination ... -
Recombination Sites on Hybrid Chromosomes in S. pastorianus share Common Sequence Motifs and define a Complex Evolutionary Relationship between Group I and II Lager Yeasts
BOND, URSULA (2017)Saccharomyces pastorianus, referred to as lager yeasts, are hybrids of S. cerevisiae and S. eubayanus. Isolates within the species are divided into two groups (I and II) based on chromosome structure and composition. ... -
Structure-function analyses of the interactions between Rab11 and Rab14 small GTPases with their shared effector Rab coupling protein (RCP)
BOND, URSULA; KHAN, AMIR (2015)Rab GTPases recruit effector proteins, via their GTP-dependent switch regions, to distinct subcellular compartments. Rab11 and Rab25 are closely related small GTPases that bind to common effectors termed the Rab11 family ...