Browsing Genetics (Theses and Dissertations) by Author "O'Neill, Brian G. D."
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Novel therapeutic strategies for autosomal dominant retinitis pigmentosa
O'Neill, Brian G. D. (Trinity College (Dublin, Ireland). School of Genetics and Microbiology, 2000)A major difficulty associated with the design of gene therapies for autosomal dominant diseases is the immense intragenic heterogeneity often encountered in such conditions. Two strategies which circumvent the difficulties ...