Browsing Genetics (Theses and Dissertations) by Subject "Gene therapy"
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A novel gene-based therapy for galaucoma:from discovery to preclinical development
(Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2018)Introduction: Glaucoma is a multifactorial condition that will often result in complete bilateral blindness if untreated. Elevated intraocular pressure (IOP) is both a major risk factor and indicator of disease. IOP is ... -
Optimisation of therapies for inherited retinal and mitochondrial diseases
Inherited retinal degenerations (IRDs) are the most frequent cause of vision loss in people of working age. They have highly varied causes and pathophysiologies, and are typically incurable. Gene therapy has emerged as a ...