Browsing Genetics (Theses and Dissertations) by Author "McMahon, Helena"
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Exploration of a therapeutic strategy for osteogenesis imperfecta
McMahon, Helena (Trinity College (Dublin, Ireland). Department of Genetics, 2007)The studies described in this thesis focus upon an RNAi-base therapeutic approach for the treatment of Col1A1 linked Osteogenesis Imperfecta (OI). OI is an autosomal dominant negative disorder in w hich the presence of ...