Browsing Biochemistry (Scholarly Publications) by Subject "Glucose metabolism"
Now showing items 1-4 of 4
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5-aminolevulinic acid (ALA) deficiency causes impaired glucose tolerance and insulin resistance coincident with an attenuation of mitochondrial function in aged mice
(2018)In vertebrates, the initial step in heme biosynthesis is the production of 5-aminolevulinic acid (ALA) by ALA synthase (ALAS). ALA formation is believed to be the rate-limiting step for cellular heme production. Recently, ... -
Early Hippocampal Synaptic Loss Precedes Neuronal Loss and Associates with Early Behavioural Deficits in Three Distinct Strains of Prion Disease
(2013)Prion diseases are fatal neurodegenerative diseases of the CNS that are associated with the accumulation of misfolded cellular prion protein. There are several different strains of prion disease defined by different patterns ... -
Interleukin-33 regulates metabolic reprogramming of the retinal pigment epithelium in response to immune stressors
(2021)It remains unresolved how retinal pigment epithelial cell metabolism is regulated following immune activation to maintain retinal homeostasis and retinal function. We exposed retinal pigment epithelium (RPE) to several ... -
Regulation of glucose metabolism in T cells: new insight into the role of phosphoinositide 3-kinases
(Frontiers in Immunology, 2012)Nai?ve T cells are relatively quiescent cells that only require energy to prevent atrophy and for survival and migration. However, in response to developmental or extrinsic cues T cells can engage in rapid growth and robust ...