Browsing Biochemistry (Scholarly Publications) by Author "Sheils, Orla"
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Suppression of Natural Killer cell NKG2D and CD226 anti-tumour cascades by platelet cloaked cancer cells: Implications for the metastatic cascade
Gardiner, Clair; O'Toole, Sharon; Sheils, Orla (2019)Tumour cell immune evasion is a principal hallmark of successful metastasis. Tumour cells in the vasculature adopt a platelet cloak that efficiently suppresses the innate immune system by directly inhibiting Natural Killer ...