Browsing Biochemistry (Scholarly Publications) by Author "Mc Entee, Craig"
Now showing items 1-4 of 4
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Alpha-galactosylceramide enhances mucosal immunity to oral whole-cell cholera vaccines
Lavelle, Edward; Mc Entee, Craig (2019)Cholera is a severe diarrheal disease caused by the bacterium Vibrio cholerae (V. cholerae) that results in 3–4 million cases globally with 100,000–150,000 deaths reported annually. Mostly confined to developing nations, ... -
Divergent roles for the IL-1 family in gastrointestinal homeostasis and inflammation
Lavelle, Edward; Finlay, Conor; Mc Entee, Craig (2019)Inflammatory disorders of the gastro-intestinal tract are a major cause of morbidity and significant burden from a health and economic perspective in industrialized countries. While the incidence of such conditions has a ... -
An oral alpha-galactosylceramide adjuvanted Helicobacter pylori vaccine induces protective IL-1R- and IL-17R-dependent Th1 responses
Lavelle, Edward; Mc Entee, Craig (2019)Helicobacter pylori causes chronic gastric infection that can lead to peptic ulcers and is an identified risk factor for gastric cancer development. Although much effort has been put into the development of a Helicobacter ... -
Type ii nkt cell agonist, sulfatide, is an effective adjuvant for oral heat-killed cholera vaccines
Lavelle, Edward; Mc Entee, Craig (2021)Oral vaccination has the potential to offer a safer and more efficacious approach for protection against enteric pathogens than injection-based approaches, especially in developing countries. One key advantage is the ...