Browsing Biochemistry (Scholarly Publications) by Author "KEANE, JOSEPH"
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Alveolar Macrophages Contribute to Respiratory Tolerance by Inducing FoxP3 Expression in Naive T Cells
MILLS, KINGSTON; KEANE, JOSEPH; RUANE, DARREN; COLEMAN, MICHELLE; MORAN, BARRY (2013)Alveolar macrophages (AMs) from mice and humans have long been known to contribute to maintaining tolerance in the lung. Studies have shown that AMs can induce anergy in CD4+ T cells. Nitric oxide, prostaglandins, and ... -
Autophagy in the immune response to tuberculosis: clinical perspectives
KEANE, JOSEPH; HARRIS, JAMES; LAVELLE, EDWARD; NI CHEALLAIGH, CLIONA; Hope, J.C. (2011)A growing body of evidence points to autophagy as an essential component in the immune response to tuberculosis. Autophagy is a direct mechanism of killing intracellular Mycobacterium tuberculosis and also acts as a modulator ...