Browsing Biochemistry (Scholarly Publications) by Author "Jakobsen, Martin R."
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Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage.
Bowie, Andrew; Dunphy, Gillian; Flannery, Sinéad M.; Almine, Jessica F.; Connolly, Dympna J.; Paulus, Christina; Jønsson, Kasper L.; Jakobsen, Martin R.; Nevels, Michael M.; Unterholzner, Leonie (2018)DNA damage can be sensed as a danger-associated molecular pattern by the innate immune system. Here we find that keratinocytes and other human cells mount an innate immune response within hours of etoposide-induced DNA ...