Browsing Biochemistry (Scholarly Publications) by Author "GARDINER, CLAIR"
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IFNL cytokines do not modulate human or murine NK cell functions
O'FARRELLY, CLIONA; GARDINER, CLAIR; WALTON, CLAIR (2014)The interferon-lambda (IFNL) cytokines have been shown to be important in HCV infection with SNPs in the IFNL3 gene associated with both natural and treatment induced viral clearance. We have recently shown that rs1299860 ... -
NK cells and psoriasis.
DUNPHY, SINEAD; GARDINER, CLAIR (2011)Psoriasis is a chronic condition of the skin characterised by distinctive scaly plaques. The immune system is now thought to play a major role in the development and pathogenesis of psoriasis with immune cells and cytokines ... -
Variation in Both IL28B and KIR2DS3 Genes Influence Pegylated Interferon and Ribavirin Hepatitis C Treatment Outcome in HIV-1 Co-Infection
GARDINER, CLAIR; WALTON, CLAIR (2013)Pegylated-IFN and ribavirin remains the current treatment for chronic HCV infection in patients co-infected with HIV-1, but this regimen has low efficacy rates, particularly for HCV genotype 1/4 infection, has severe side ... -
What Fuels Natural Killers? Metabolism and NK Cell Responses
FINLAY, DAVID; GARDINER, CLAIR (2017)