Browsing Biochemistry (Scholarly Publications) by Author "CARPENTER, SUSAN"
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Detecting microRNA activity from gene expression data.
O'NEILL, LUKE; CARPENTER, SUSAN (2010)ABSTRACT: BACKGROUND: MicroRNAs (miRNAs) are non-coding RNAs that regulate gene expression by binding to the messenger RNA (mRNA) of protein coding genes. They control gene expression by either inhibiting translation or ... -
Glucocorticoids inhibit IRF3 phosphorylation in response to Toll-like
O'NEILL, LUKE ANTHONY JOHN; CARPENTER, SUSAN; PALSSON MCDERMOTT, EVA (2008)Phosphorylation of the transcription factor interferon regulatory factor 3 (IRF3) is essential for the induction of promoters which contain the interferon-stimulated response element (ISRE). IRF3 can be activated by Toll-like ... -
Toll-like receptor (TLR) 3 signaling requires the TLR4 interactor with leucine-rich repeats (TRIL).
CARPENTER, SUSAN; DUNNE, AISLING; O'NEILL, LUKE (2011)Toll-like (TLRs) receptors are a family of proteins that act as the primary sensors of microbial products. Many TLRs require accessory molecules in order to recognize these microbial products and initiate signal transduction ...