Browsing Biochemistry (Theses and Dissertations) by Sponsor "Marie Curie"
Now showing items 1-4 of 4
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Evidence of a role for Interleukin-6 in anoikis resistance and bioenergetic programming in oral squamous cell carcinoma
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2021)Oral squamous cell carcinoma (OSCC) is the sixth most common type of cancer in the world and accounts for more than 90% of oral malignancies. Oral squamous cell carcinomas are usually preceded by oral premalignant ... -
Identification of novel innate immune mechanisms regulating oesophageal adenocarcinoma (OAC) progression and bacterial infection
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)Inflammation is an essential immune system response to pathogens, damaged cells and stress stimuli and has an essential role in tissue repair and regeneration. The inflammatory response is the coordinated activation of ... -
In-depth Analytical Platforms Facilitating Serum Glycome, Proteome and Glycoproteome Investigation for Biomarker Discovery
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)Human serum is a great source of potential protein disease biomarkers because of how blood interacts with all parts of the body, allowing it to contain proteins secreted from specific tissues of interest, and due the ... -
Molecular investigation of mitophagy in neuronal cell models
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)Autophagy functions as a cellular recycling and quality control pathway and is likely responsible for maintenance of viable mitochondria by mitophagy, even though exact mechanisms remain unclear. Mitophagy is characterised ...