Browsing Biochemistry (Theses and Dissertations) by Author "Ross, Pádraig John"
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Modulation of innate and adaptive immune responses by adenylate cyclase toxin from Bordetella pertussis
Ross, Pádraig John (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2006)CyaA belongs to the repeat-in-toxin (RTX) family of pore-forming toxins that require posttranslational acyiation to lyse eukaryotic cells. While it was known that CyaA binds to a variety of cell types, catalyses the ...