Browsing Biochemistry (Theses and Dissertations) by Author "Kelly, Patrick Joseph"

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  • The immunomodulatory effects of NOD1 activation 

    Kelly, Patrick Joseph (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2014)
    NOD1 and NOD2 are cytosolic pathogen recognition receptors (PRRs) which detect peptidoglycan derivatives and contribute to the host defence during bacterial infection. Transgenic mice lacking NOD1 or NOD2 are susceptible ...