Browsing Biochemistry (Theses and Dissertations) by Author "Dunican, Donncha St. John"
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Differential patterns of gene expression associated with microsatellite instability and chromosomal instability in colorectal cancer
Dunican, Donncha St. John (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2000)Two distinct pathways exist in sporadic colorectal cancer. The microsatellite instability pathway (MIN) is recognised by widespread instability caused by aberrant mismatch repair machinery. This genotype accounts for 15% ...