Browsing Biochemistry (Theses and Dissertations) by Author "Boland, Coilín"
Now showing items 1-1 of 1
-
Identification of the mammalian queuine transfer RNA ribosyltransferase complex and characterisation of QTRT1 gene-trap mice deficient in queuosine modified transfer RNA
Boland, Coilín (Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2010)Queuine, or Q-base, is a modified form of 7-deazaguanine that is synthesised de novo by eubacteria, but which is obtained from food or the gut flora by eukaryotes. Q-base is enzymatically inserted into the wobble position ...