Browsing Clinical Microbiology (Theses and Dissertations) by Title

Now showing items 23-28 of 28

    • Regulation of Antigen 43, a phase-variable autoaggregation factor of Escherichia coli 

      Waldron, Denise Ethel (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2003)
      The Antigen 43 protein (Ag43) of Escherichia coli, encoded by the agn43 gene, has previously been shown to be expressed in a phase-variable manner. A plasmidborne fusion of the agn43 regulatory region to the reporter gene ...

    • StpA and the regulation of OmpF porin expression in Escherichia coli 

      Deighan, Padraig (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2001)
      When the proteomic profile of a wild-type strain of Escherichia coli and its stpA hns mutant derivative were compared by two-dimensional gel electrophoresis, the levels of expression of several proteins were altered. One ...

    • The control of DNA gyrase expression and its role in deletion formation in Salmonella enterica 

      Keane, Orla Mary (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2003)
      Salmonella typhimurium strain CJD671 can undergo the deletion of a 5kb segment of DNA from its large virulence plasmid. This results in a transcriptional fusion between the rlgA gene, encoding a putative site-specific ...

    • The molecular characterization of the clumping Factor A (ClfA) from Staphylococcus aureus using monoclonal antibodies 

      McNamara, Gillian (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2000)
      Clumping factor (ClfA) of Staphylococcus aureus is the major fibrinogen- binding adhesin located on the cell surface of the bacterium. Monoclonal antibodies (mAbs) were produced to two recombinant truncated ClfA proteins, ...

    • The role of beta-lactamase in low-level cephalosporin-resistant serratia marcescens 

      Herra, Celine M. (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2002)
      In enterobacteria, high-level cephalosporin resistance is commonly mediated by constitutive over-production or derepression of chromosomal AmpC β-lactamase. This derepression is frequently associated with mutations in ...

    • The role of the Salmonella PagN protein in adhesion and invasion 

      Paré, Samantha E. (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2015)
      Salmonella, an important genus of Gram-negative enteric bacteria, is the causative agent of many different diseases including Typhoid Fever and Gastroenteritis. Salmonella utilises multiple methods of invading mammalian ...