Browsing Physiology (Scholarly Publications) by Subject "Age"
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CD200 fusion protein decreases microglial activation in the hippocampus of aged rats
(2012)The glycoprotein, CD200, is primarily expressed on neurons and its cognate receptor CD200R is expressed principally on cells of the myeloid lineage, including microglia. The interaction of CD200 with its receptor plays a ... -
Exploring Sex-Related Differences in Microglia May Be a Game-Changer in Precision Medicine
(2022)One area of microglial biology that has been relatively neglected until recently is sex differences and this is in spite of the fact that sex is a risk factor in several diseases that are characterized by neuroinflammation ... -
How dependent is synaptic plasticity on microglial phenotype?
(2015)Microglia are particularly plastic cells which can be shifted from their resting state by numerous factors and adopt distinct phenotypes. The cells are multifunctional, though their main role is probably maintenance of ...